Genopathy
Gene-Disorder Association · Article
Gene
AKT2
AKT Serine/Threonine Kinase 2
Disorder
Ovarian Cancer
First reported 1992
Supporting publications 15
Key publication · gene–disorder AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.Proceedings of the National Academy of Sciences of the United States of America · 1992
Key publication · disorder Ovarian cancer in mother and five daughters.A.M.A. archives of pathology · 1950
Manually curated
Association Review

In brief

The association between AKT2 (AKT Serine/Threonine Kinase 2) and Ovarian Cancer is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 8
Compounds 0
Trials 0
Publications 15
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access
02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access
03
AKT2

The gene

2 source summaries

A gene summary alongside the source descriptions it was distilled from.

Request access
04
Ovarian Cancer

The disorder

19 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access
05
Phenotype

Clinical features

3 clinical features

The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.

Request access
06
Literature

Reading

15 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

Request access
07
Provenance

References & sources

14 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access