CDK4 and Dedifferentiated Liposarcoma: Association Evidence

Gene-Disorder Association · Article

Gene

CDK4

Cyclin Dependent Kinase 4

Disorder

First reported 2003

Supporting publications 12

Key publication · gene–disorder Most malignant fibrous histiocytomas developed in the retroperitoneum are dedifferentiated liposarcomas: a review of 25 cases initially diagnosed as malignant fibrous histiocytoma.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2003

Key publication · disorder S-100 protein distribution in liposarcoma. An immunoperoxidase study with special reference to the distinction of liposarcoma from myxoid malignant fibrous histiocytoma.Virchows Archiv. A, Pathological anatomy and histopathology · 1984

Manually curated

Association Review

In brief

The association between CDK4 (Cyclin Dependent Kinase 4) and Dedifferentiated Liposarcoma is a manually-curated gene–disease association, supported by a single expert-curated source.

Sources 1

Clinical variants 0

Symptoms 0

Compounds 0

Trials 0

Publications 12

At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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CDK4

The gene

3 source summaries

A gene summary alongside the source descriptions it was distilled from.

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Dedifferentiated Liposarcoma

The disorder

6 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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Literature

Reading

12 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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Provenance

References & sources

13 references

Every source and publication cited across this dossier, as one numbered reference list.

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