Genopathy
Gene-Disorder Association · Article
Gene
CYP3A5
Cytochrome P450 Family 3 Subfamily A Member 5
Manually curatedApproved treatment annotated
Association Review

In brief

The association between CYP3A5 (Cytochrome P450 Family 3 Subfamily A Member 5) and Major Depressive Disorder is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 3
Compounds 14
Trials 181of 2,034 via CYP3A5 compounds
Publications 0
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
CYP3A5

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

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04
Major Depressive Disorder

The disorder

14 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
Phenotype

Clinical features

1 clinical feature

The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.

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06
Interventions

Therapeutics

14 compounds & drugs

Gene-targeting drugs and associated compounds, with class, approval status, mechanism, indications and trials.

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07
Human studies

Clinical trials

2,034 clinical trials

Clinical trials reached through the pair’s compounds, keeping disorder-targeting trials separate from other indications.

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08
Provenance

References & sources

6 references

Every source and publication cited across this dossier, as one numbered reference list.

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