Genopathy
Gene-Disorder Association · Article
Gene
DDB2
Damage Specific DNA Binding Protein 2
Disorder
Melanoma
First reported 2008
Supporting publications 1
Key publication · gene–disorder Defective cell cycle checkpoint functions in melanoma are associated with altered patterns of gene expression.The Journal of investigative dermatology · 2008
Key publication · disorder The properties and surgical problems of malignant melanoma.Annals of the Royal College of Surgeons of England · 1950
Manually curated
Association Review

In brief

The association between DDB2 (Damage Specific DNA Binding Protein 2) and Melanoma is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 2
Compounds 0
Trials 0
Publications 1
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access
02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access
03
DDB2

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

Request access
04
Melanoma

The disorder

7 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access
05
Mechanism overlap

Shared mechanisms

1 shared pathway

Biological pathways and phenotype concepts shared by the gene and the disorder, with supporting publications.

Request access
06
Literature

Reading

1 publication

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

Request access
07
Provenance

References & sources

8 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access