Genopathy
Gene-Disorder Association · Article
Gene
DNAJC21
DnaJ Heat Shock Protein Family (Hsp40) Member C21
Disorder
Leukemia, Acute Myeloid
First reported 1950
Key publication · disorder [Septic pharyngeal diphtheria followed by acute myeloid leukemia].Osterreichische Zeitschrift fur Kinderheilkunde und Kinderfursorge · 1950
Manually curated
Association Review

In brief

The association between DNAJC21 (DnaJ Heat Shock Protein Family (Hsp40) Member C21) and Leukemia, Acute Myeloid is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 5
Compounds 0
Trials 0
Publications 0
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
DNAJC21

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

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04
Leukemia, Acute Myeloid

The disorder

27 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
Phenotype

Clinical features

1 clinical feature

The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.

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06
Mechanism overlap

Shared mechanisms

Biological pathways and phenotype concepts shared by the gene and the disorder, with supporting publications.

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07
Provenance

References & sources

6 references

Every source and publication cited across this dossier, as one numbered reference list.

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