Gene-Disorder Association · Article
Gene
DPP6 Dipeptidyl Peptidase Like 6
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First reported
1950
Supporting publications
1
Approved treatment annotated
Association Review
In brief The association between DPP6 (Dipeptidyl Peptidase Like 6) and Schizophrenia is supported by expert-curated evidence, drawing on a single expert-curated source, which records likely-pathogenic variants.
Sources
1
Clinical variants
0
Symptoms
15
Compounds
1
Trials
45 of 142 via DPP6 compounds
Publications
1
Contents
01
At a glance
Association overview A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.
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Provenance
Evidence and sources 1 source
Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.
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A gene summary alongside the source descriptions it was distilled from.
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Schizophrenia
The disorder 13 database identifiers
The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).
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Phenotype
Clinical features 6 clinical features
The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.
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Population genetics
GWAS signals 1 GWAS phenotype
Gene-associated GWAS phenotypes matching the disorder, with best SNP, score, risk-allele frequency and effect size.
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Interventions
Therapeutics 1 compound or drug
Gene-targeting drugs and associated compounds, with class, approval status, mechanism, indications and trials.
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Human studies
Clinical trials 142 clinical trials
Clinical trials reached through the pair’s compounds, keeping disorder-targeting trials separate from other indications.
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Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.
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Provenance
References & sources 9 references
Every source and publication cited across this dossier, as one numbered reference list.
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