Gene-Disorder Association · Article
Gene
ERBB2 Erb-B2 Receptor Tyrosine Kinase 2
×
First reported
1995
Supporting publications
16
Manually curated Approved treatment annotated
Association Review
In brief The association between ERBB2 (Erb-B2 Receptor Tyrosine Kinase 2) and Squamous Cell Carcinoma, Head And Neck is reported, with clinical genetic testing available.
Sources
1
Clinical variants
0
Symptoms
9
Compounds
6
Trials
566 of 9,257 via ERBB2 compounds
Publications
16
Contents
01
At a glance
Association overview A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.
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Provenance
Evidence and sources 1 source
Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.
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A gene summary alongside the source descriptions it was distilled from.
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Squamous Cell Carcinoma, Head And Neck
The disorder 32 database identifiers
The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).
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Phenotype
Clinical features 1 clinical feature
The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.
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Interventions
Therapeutics 6 compounds & drugs
Gene-targeting drugs and associated compounds, with class, approval status, mechanism, indications and trials.
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Human studies
Clinical trials 9,257 clinical trials
Clinical trials reached through the pair’s compounds, keeping disorder-targeting trials separate from other indications.
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Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.
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Provenance
References & sources 17 references
Every source and publication cited across this dossier, as one numbered reference list.
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