Genopathy
Gene-Disorder Association · Article
Gene
ERBB3
Erb-B2 Receptor Tyrosine Kinase 3
Disorder
Gastric Cancer
First reported 2008
Supporting publications 5
Key publication · gene–disorder High expression of HER3 is associated with a decreased survival in gastric cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2008
Key publication · disorder Mortality from and risk of gastric carcinoma among patients with pernicious anaemia.British medical journal · 1950
Manually curated
Association Review

In brief

The association between ERBB3 (Erb-B2 Receptor Tyrosine Kinase 3) and Gastric Cancer is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 10
Compounds 0
Trials 0
Publications 5
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
ERBB3

The gene

2 source summaries

A gene summary alongside the source descriptions it was distilled from.

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04
Gastric Cancer

The disorder

31 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
Phenotype

Clinical features

2 clinical features

The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.

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06
Literature

Reading

5 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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07
Provenance

References & sources

10 references

Every source and publication cited across this dossier, as one numbered reference list.

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