Genopathy
Gene-Disorder Association · Article
Gene
EZH2
Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit
Disorder
Lymphoma, Hodgkin, Classic
First reported 2000
Supporting publications 1
Key publication · gene–disorder Coexpression of BMI-1 and EZH2 polycomb group genes in Reed-Sternberg cells of Hodgkin's disease.The American journal of pathology · 2000
Key publication · disorder [Cutaneous manifestations in Hodgkin disease and lymphosarcomatosis].Anales de la Facultad de Medicina, Universidad de la Republica, Montevideo, Uruguay · 1952
Manually curated
Association Review

In brief

The association between EZH2 (Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit) and Lymphoma, Hodgkin, Classic is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 39
Compounds 0
Trials 0
Publications 1
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
EZH2

The gene

2 source summaries

A gene summary alongside the source descriptions it was distilled from.

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04
Lymphoma, Hodgkin, Classic

The disorder

17 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
Phenotype

Clinical features

35 clinical features

The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.

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06
Literature

Reading

1 publication

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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07
Provenance

References & sources

8 references

Every source and publication cited across this dossier, as one numbered reference list.

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