Genopathy
Gene-Disorder Association · Article
Gene
F11
Coagulation Factor XI
Disorder
Hemophilia A
First reported 1999
Key publication · gene–disorder Women and inherited bleeding disorders: pregnancy and delivery.Seminars in hematology · 1999
Key publication · disorder The Consumption of Prothrombin during Coagulation: The Defect in Haemophilia and Thrombo-Cytopenic Purpura.Journal of clinical pathology · 1950
Manually curated
Association Review

In brief

The association between F11 (Coagulation Factor XI) and Hemophilia A is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 60
Compounds 0
Trials 0
Publications 0
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access
02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access
03
F11

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

Request access
04
Hemophilia A

The disorder

18 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access
05
Phenotype

Clinical features

50 clinical features

The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.

Request access
06
Mechanism overlap

Shared mechanisms

Biological pathways and phenotype concepts shared by the gene and the disorder, with supporting publications.

Request access
07
Provenance

References & sources

6 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access