Genopathy
Gene-Disorder Association · Article
Gene
FH
Fumarate Hydratase
Disorder
Renal Cell Carcinoma
First reported 2002
Supporting publications 30
Key publication · gene–disorder Few FH mutations in sporadic counterparts of tumor types observed in hereditary leiomyomatosis and renal cell cancer families.Cancer research · 2002
Key publication · disorder Polycythaemia vera; coexisting with malignant tumours (particularly hypernephroma).Acta medica Scandinavica · 1950
Manually curated
Association Review

In brief

The association between FH (Fumarate Hydratase) and Renal Cell Carcinoma is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 1
Compounds 0
Trials 0
Publications 30
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
FH

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

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04
Renal Cell Carcinoma

The disorder

8 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
Mechanism overlap

Shared mechanisms

1 shared pathway

Biological pathways and phenotype concepts shared by the gene and the disorder, with supporting publications.

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06
Literature

Reading

30 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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07
Provenance

References & sources

14 references

Every source and publication cited across this dossier, as one numbered reference list.

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