Genopathy
Gene-Disorder Association · Article
Gene
FLT3
Fms Related Receptor Tyrosine Kinase 3
Manually curatedApproved treatment annotated
Association Review

In brief

The association between FLT3 (Fms Related Receptor Tyrosine Kinase 3) and Acute Myeloid Leukemia Without Maturation is a manually-curated gene–disease association, drawing on a single expert-curated source, which records causative variation.

Sources 1
Clinical variants 0
Symptoms 0
Compounds 8
Trials 1,033of 4,103 via FLT3 compounds
Publications 1
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access
02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access
03
FLT3

The gene

3 source summaries

A gene summary alongside the source descriptions it was distilled from.

Request access
04
Acute Myeloid Leukemia Without Maturation

The disorder

9 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access
05
Interventions

Therapeutics

8 compounds & drugs

Gene-targeting drugs and associated compounds, with class, approval status, mechanism, indications and trials.

Request access
06
Human studies

Clinical trials

4,103 clinical trials

Clinical trials reached through the pair’s compounds, keeping disorder-targeting trials separate from other indications.

Request access
07
Literature

Reading

1 publication

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

Request access
08
Provenance

References & sources

8 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access