Genopathy
Gene-Disorder Association · Article
Gene
GABBR2
Gamma-Aminobutyric Acid Type B Receptor Subunit 2
Manually curated
Association Review

In brief

The association between GABBR2 (Gamma-Aminobutyric Acid Type B Receptor Subunit 2) and Tobacco Addiction is well established and manually curated, with its 3 contributing sources — 2 of them expert-curated — recording a known molecular basis and a susceptibility locus.

Sources 3
Clinical variants 6
Symptoms 1
Compounds 0
Trials 0
Publications 1
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access
02
Provenance

Evidence and sources

3 sources

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access
03
GABBR2

The gene

2 source summaries

A gene summary alongside the source descriptions it was distilled from.

Request access
04
Tobacco Addiction

The disorder

10 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access
05
Phenotype

Clinical features

1 clinical feature

The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.

Request access
06
ClinVar and variant evidence

Genetic basis

6 clinical variants

ClinVar variants reported for this pair, with disorder-specific significance, review status, molecular consequence and origin.

Request access
07
Literature

Reading

1 publication

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

Request access
08
Provenance

References & sources

6 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access