Genopathy
Gene-Disorder Association · Article
Gene
GCH1
GTP Cyclohydrolase 1
Disorder
Movement Disease
First reported 2005
Supporting publications 3
Key publication · gene–disorder Mapping of a new form of pure autosomal recessive spastic paraplegia (SPG28).Annals of neurology · 2005
Key publication · disorder [The late result of surgery of extrapyramidal movement disorders and paraplegias].Deutsche Zeitschrift fur Nervenheilkunde · 1952
Manually curated
Association Review

In brief

The association between GCH1 (GTP Cyclohydrolase 1) and Movement Disease is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 28
Compounds 0
Trials 0
Publications 3
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
GCH1

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

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04
Movement Disease

The disorder

6 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
Literature

Reading

3 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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06
Provenance

References & sources

6 references

Every source and publication cited across this dossier, as one numbered reference list.

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