Genopathy
Gene-Disorder Association · Article
Gene
HCN2
Hyperpolarization Activated Cyclic Nucleotide Gated Potassium And Sodium Channel 2
Disorder
Epilepsy
First reported 2010
Supporting publications 1
Key publication · gene–disorder Augmented currents of an HCN2 variant in patients with febrile seizure syndromes.Annals of neurology · 2010
Key publication · disorder [Differential diagnosis of genuine and so-called traumatic epilepsy].Archiv fur Psychiatrie und Nervenkrankheiten, vereinigt mit Zeitschrift fur die gesamte Neurologie und Psychiatrie · 1950
Manually curated
Association Review

In brief

The association between HCN2 (Hyperpolarization Activated Cyclic Nucleotide Gated Potassium And Sodium Channel 2) and Epilepsy is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 11
Compounds 0
Trials 0
Publications 1
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access
02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access
03
HCN2

The gene

2 source summaries

A gene summary alongside the source descriptions it was distilled from.

Request access
04
Epilepsy

The disorder

11 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access
05
Literature

Reading

1 publication

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

Request access
06
Provenance

References & sources

5 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access