Association Review
In brief
The association between IL10 (Interleukin 10) and Inflammatory Bowel Disease is reported, with clinical genetic testing available.
Sources
1
Clinical variants
119
Symptoms
0
Compounds
0
Trials
0
Publications
19
01
At a glance
Association overview
A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.
02
Provenance
Evidence and sources
1 source
Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.
1 source summary
A gene summary alongside the source descriptions it was distilled from.
04
Inflammatory Bowel Disease
The disorder
6 database identifiers
The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).
05
ClinVar and variant evidence
Genetic basis
119 clinical variants
ClinVar variants reported for this pair, with disorder-specific significance, review status, molecular consequence and origin.
06
Population genetics
GWAS signals
1 GWAS phenotype
Gene-associated GWAS phenotypes matching the disorder, with best SNP, score, risk-allele frequency and effect size.
07
Mechanism overlap
Shared mechanisms
2 shared pathways
Biological pathways and phenotype concepts shared by the gene and the disorder, with supporting publications.
19 publications
Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.
09
Provenance
References & sources
16 references
Every source and publication cited across this dossier, as one numbered reference list.
