Association Review
In brief
The association between IL2RA (Interleukin 2 Receptor Subunit Alpha) and Type 1 Diabetes Mellitus is reported, supported by a single source.
Sources
1
Clinical variants
0
Symptoms
13
Compounds
0
Trials
0
Publications
1
01
At a glance
Association overview
A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.
02
Provenance
Evidence and sources
1 source
Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.
2 source summaries
A gene summary alongside the source descriptions it was distilled from.
04
Type 1 Diabetes Mellitus
The disorder
10 database identifiers
The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).
05
Phenotype
Clinical features
8 clinical features
The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.
06
Population genetics
GWAS signals
2 GWAS phenotypes
Gene-associated GWAS phenotypes matching the disorder, with best SNP, score, risk-allele frequency and effect size.
07
Genomic context
Regulatory context
1 regulatory element
GeneHancer regulatory elements for the pair, with coordinates, score, element type and supporting literature.
08
Mechanism overlap
Shared mechanisms
Biological pathways and phenotype concepts shared by the gene and the disorder, with supporting publications.
1 publication
Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.
10
Provenance
References & sources
9 references
Every source and publication cited across this dossier, as one numbered reference list.
