Genopathy
Gene-Disorder Association · Article
Gene
IRAK3
Interleukin 1 Receptor Associated Kinase 3
Disorder
Multisystem Inflammatory Syndrome In Children
First reported 1975
Key publication · disorder The relationship of disturbing life-changes and emotions to the early development of myocardial infarction and other serious illnesses.International journal of epidemiology · 1975
Association Review

In brief

The association between IRAK3 (Interleukin 1 Receptor Associated Kinase 3) and Multisystem Inflammatory Syndrome In Children is supported by expert-curated evidence, supported by a single expert-curated source.

Sources 1
Clinical variants 1
Symptoms 0
Compounds 0
Trials 0
Publications 0
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
IRAK3

The gene

2 source summaries

A gene summary alongside the source descriptions it was distilled from.

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04
Multisystem Inflammatory Syndrome In Children

The disorder

3 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
ClinVar and variant evidence

Genetic basis

1 clinical variant

ClinVar variants reported for this pair, with disorder-specific significance, review status, molecular consequence and origin.

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06
Provenance

References & sources

3 references

Every source and publication cited across this dossier, as one numbered reference list.

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