Genopathy
Gene-Disorder Association · Article
Gene
LDB3
LIM Domain Binding 3
Disorder
Left Ventricular Noncompaction
First reported 1960
Key publication · disorder [On the behavior of glucose, glucose-1-phosphate and glycogen in the maternal and fetal myocardium].Archivio "E. Maragliano" di patologia e clinica · 1960
Manually curated
Association Review

In brief

The association between LDB3 (LIM Domain Binding 3) and Left Ventricular Noncompaction is well established and manually curated, with its 2 contributing sources — 1 of them expert-curated — recording a susceptibility locus.

Sources 2
Clinical variants 25
Symptoms 0
Compounds 0
Trials 0
Publications 0
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access
02
Provenance

Evidence and sources

2 sources

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access
03
LDB3

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

Request access
04
Left Ventricular Noncompaction

The disorder

8 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access
05
ClinVar and variant evidence

Genetic basis

25 clinical variants

ClinVar variants reported for this pair, with disorder-specific significance, review status, molecular consequence and origin.

Request access
06
Provenance

References & sources

5 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access