Genopathy
Gene-Disorder Association · Article
Gene
LZTR1
Leucine Zipper Like Post Translational Regulator 1
Disorder
Legius Syndrome
First reported 1978
Key publication · disorder A least-squares technique for extracting neutron spectra from Bonner sphere data.Medical physics · 1978
Manually curated
Association Review

In brief

The association between LZTR1 (Leucine Zipper Like Post Translational Regulator 1) and Legius Syndrome is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 75
Compounds 0
Trials 0
Publications 0
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access
02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access
03
LZTR1

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

Request access
04
Legius Syndrome

The disorder

12 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access
05
Phenotype

Clinical features

58 clinical features

The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.

Request access
06
Mechanism overlap

Shared mechanisms

Biological pathways and phenotype concepts shared by the gene and the disorder, with supporting publications.

Request access
07
Provenance

References & sources

6 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access