Genopathy
Gene-Disorder Association · Article
Gene
MIF
Macrophage Migration Inhibitory Factor
Disorder
Rheumatoid Arthritis, Systemic Juvenile
First reported 2001
Supporting publications 2
Key publication · gene–disorder A novel 5'-flanking region polymorphism of macrophage migration inhibitory factor is associated with systemic-onset juvenile idiopathic arthritis.Arthritis and rheumatism · 2001
Key publication · disorder Iridocyclitis and bandshaped corneal opacity in juvenile rheumatoid arthritis.Acta ophthalmologica · 1950
Manually curated
Association Review

In brief

The association between MIF (Macrophage Migration Inhibitory Factor) and Rheumatoid Arthritis, Systemic Juvenile is well established and manually curated, with its 2 contributing sources — 2 of them expert-curated — recording a known molecular basis and a susceptibility locus.

Sources 2
Clinical variants 0
Symptoms 3
Compounds 0
Trials 0
Publications 2
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

2 sources

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
MIF

The gene

2 source summaries

A gene summary alongside the source descriptions it was distilled from.

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04
Rheumatoid Arthritis, Systemic Juvenile

The disorder

24 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
Literature

Reading

2 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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06
Provenance

References & sources

8 references

Every source and publication cited across this dossier, as one numbered reference list.

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