Genopathy
Gene-Disorder Association · Article
Gene
MIR17HG
MiR-17-92a-1 Cluster Host Gene
Disorder
Feingold Syndrome 2
First reported 2013
Supporting publications 2
Key publication · gene–disorder De novo 13q31.1-q32.1 interstitial deletion encompassing the miR-17-92 cluster in a patient with Feingold syndrome-2.American journal of medical genetics. Part A · 2013
Key publication · disorder [The phenotype of the trisomy of the short arm of chromosome no. 4. (a new case with t (4p; 11q) (author's transl)].Klinische Padiatrie · 1976
Manually curated
Association Review

In brief

The association between MIR17HG (MiR-17-92a-1 Cluster Host Gene) and Feingold Syndrome 2 is well established and manually curated, with its 3 contributing sources — 2 of them expert-curated — recording pathogenic variants and a causative germline mutation.

Sources 3
Clinical variants 0
Symptoms 33
Compounds 0
Trials 0
Publications 2
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

3 sources

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
MIR17HG

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

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04
Feingold Syndrome 2

The disorder

10 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
Phenotype

Clinical features

22 clinical features

The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.

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06
Mechanism overlap

Shared mechanisms

Biological pathways and phenotype concepts shared by the gene and the disorder, with supporting publications.

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07
Literature

Reading

2 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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08
Provenance

References & sources

9 references

Every source and publication cited across this dossier, as one numbered reference list.

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