Genopathy
Gene-Disorder Association · Article
Gene
MIR221
MicroRNA 221
Disorder
Pancreatic Cancer
First reported 2006
Supporting publications 2
Key publication · gene–disorder A microRNA expression signature of human solid tumors defines cancer gene targets.Proceedings of the National Academy of Sciences of the United States of America · 2006
Key publication · disorder Pancreatic carcinoma with unusual metastasis to the skin and subcutaneous tissue simulating cellulitis.The New England journal of medicine · 1950
Manually curated
Association Review

In brief

The association between MIR221 (MicroRNA 221) and Pancreatic Cancer is reported, supported by a single source.

Sources 1
Clinical variants 0
Symptoms 35
Compounds 0
Trials 0
Publications 2
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
MIR221

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

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04
Pancreatic Cancer

The disorder

33 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
Phenotype

Clinical features

26 clinical features

The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.

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06
Literature

Reading

2 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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07
Provenance

References & sources

9 references

Every source and publication cited across this dossier, as one numbered reference list.

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