Genopathy
Gene-Disorder Association · Article
Gene
MLH1
MutL Homolog 1
Disorder
Hematologic Cancer
First reported 2006
Supporting publications 4
Key publication · gene–disorder A novel MLH1 mutation harbored as a germ line aberration by a young woman of an HNPCC-like family and exhibited by a CML patient when occurring prior to the initiation of the blast phase concomitant with a c-MYC amplification.International journal of molecular medicine · 2006
Key publication · disorder [Leukemia, control of blood cancer].Revista. Asociacion Medica Mexicana · 1952
Manually curated
Association Review

In brief

The association between MLH1 (MutL Homolog 1) and Hematologic Cancer is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 0
Compounds 0
Trials 0
Publications 4
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access
02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access
03
MLH1

The gene

2 source summaries

A gene summary alongside the source descriptions it was distilled from.

Request access
04
Hematologic Cancer

The disorder

8 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access
05
Literature

Reading

4 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

Request access
06
Provenance

References & sources

7 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access