Genopathy
Gene-Disorder Association · Article
Gene
MLLT10
MLLT10 Histone Lysine Methyltransferase DOT1L Cofactor
Disorder
Hematologic Cancer
First reported 2002
Supporting publications 3
Key publication · gene–disorder The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex.Blood · 2002
Key publication · disorder [Leukemia, control of blood cancer].Revista. Asociacion Medica Mexicana · 1952
Manually curated
Association Review

In brief

The association between MLLT10 (MLLT10 Histone Lysine Methyltransferase DOT1L Cofactor) and Hematologic Cancer is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 0
Compounds 0
Trials 0
Publications 3
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
MLLT10

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

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04
Hematologic Cancer

The disorder

8 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
Population genetics

GWAS signals

1 GWAS phenotype

Gene-associated GWAS phenotypes matching the disorder, with best SNP, score, risk-allele frequency and effect size.

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06
Literature

Reading

3 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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07
Provenance

References & sources

6 references

Every source and publication cited across this dossier, as one numbered reference list.

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