Gene-Disorder Association · Article
Gene
MTR 5-Methyltetrahydrofolate-Homocysteine Methyltransferase
×
First reported
1997
Supporting publications
1
Manually curated Approved treatment annotated
Association Review
In brief The association between MTR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase) and Protein-Deficiency Anemia is reported, with clinical genetic testing available.
Sources
1
Clinical variants
0
Symptoms
3
Compounds
2
Trials
3 of 92 via MTR compounds
Publications
1
Contents
01
At a glance
Association overview A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.
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02
Provenance
Evidence and sources 1 source
Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.
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1 source summary
A gene summary alongside the source descriptions it was distilled from.
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04
Protein-Deficiency Anemia
The disorder 20 database identifiers
The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).
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05
Interventions
Therapeutics 2 compounds & drugs
Gene-targeting drugs and associated compounds, with class, approval status, mechanism, indications and trials.
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06
Human studies
Clinical trials 92 clinical trials
Clinical trials reached through the pair’s compounds, keeping disorder-targeting trials separate from other indications.
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1 publication
Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.
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08
Provenance
References & sources 6 references
Every source and publication cited across this dossier, as one numbered reference list.
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