Genopathy
Gene-Disorder Association · Article
Gene
NOD2
Nucleotide Binding Oligomerization Domain Containing 2
Disorder
Psoriatic Arthritis
First reported 2003
Supporting publications 7
Key publication · gene–disorder CARD15: a pleiotropic autoimmune gene that confers susceptibility to psoriatic arthritis.American journal of human genetics · 2003
Key publication · disorder The effects of cortisone and adrenocorticotropic hormone (ACTH) on certain rheumatic diseases.California medicine · 1950
Manually curated
Association Review

In brief

The association between NOD2 (Nucleotide Binding Oligomerization Domain Containing 2) and Psoriatic Arthritis is reported, with clinical genetic testing available.

Sources 1
Clinical variants 8
Symptoms 3
Compounds 0
Trials 0
Publications 7
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
NOD2

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

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04
Psoriatic Arthritis

The disorder

10 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
ClinVar and variant evidence

Genetic basis

8 clinical variants

ClinVar variants reported for this pair, with disorder-specific significance, review status, molecular consequence and origin.

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06
Literature

Reading

7 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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07
Provenance

References & sources

11 references

Every source and publication cited across this dossier, as one numbered reference list.

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