Genopathy
Gene-Disorder Association · Article
Gene
NTRK3
Neurotrophic Receptor Tyrosine Kinase 3
Disorder
Lung Cancer Susceptibility 3
First reported 2007
Supporting publications 1
Key publication · gene–disorder The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas.Molecular and cellular biochemistry · 2007
Key publication · disorder WEEKLY clinicopathological exercises; metastatic adenocarcinoma of lung, from intestine.The New England journal of medicine · 1951
Manually curated
Association Review

In brief

The association between NTRK3 (Neurotrophic Receptor Tyrosine Kinase 3) and Lung Cancer Susceptibility 3 is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 0
Compounds 0
Trials 0
Publications 1
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
NTRK3

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

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04
Lung Cancer Susceptibility 3

The disorder

10 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
Literature

Reading

1 publication

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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06
Provenance

References & sources

3 references

Every source and publication cited across this dossier, as one numbered reference list.

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