Genopathy
Gene-Disorder Association · Article
Gene
ODC1
Ornithine Decarboxylase 1
Disorder
Colorectal Cancer
First reported 1991
Supporting publications 41
Key publication · gene–disorder Influence of gastrin, gastrin receptor blockers, epidermal growth factor, and difluoromethylornithine on the growth and the activity of ornithine decarboxylase of colonic carcinoma cells.Journal of cancer research and clinical oncology · 1991
Key publication · disorder A review of colon cancer; presentation of 14 cases concerning cancer of the colon.Virginia medical monthly · 1950
Manually curated
Association Review

In brief

The association between ODC1 (Ornithine Decarboxylase 1) and Colorectal Cancer is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 15
Compounds 0
Trials 0
Publications 41
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
ODC1

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

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04
Colorectal Cancer

The disorder

23 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
Phenotype

Clinical features

6 clinical features

The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.

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06
Literature

Reading

41 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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07
Provenance

References & sources

13 references

Every source and publication cited across this dossier, as one numbered reference list.

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