Genopathy
Gene-Disorder Association · Article
Gene
PIK3C2B
Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Beta
Disorder
Ovarian Cancer
First reported 1950
Key publication · disorder Ovarian cancer in mother and five daughters.A.M.A. archives of pathology · 1950
Manually curated
Association Review

In brief

The association between PIK3C2B (Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Beta) and Ovarian Cancer is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 8
Compounds 0
Trials 0
Publications 0
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access
02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access
03
PIK3C2B

The gene

2 source summaries

A gene summary alongside the source descriptions it was distilled from.

Request access
04
Ovarian Cancer

The disorder

19 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access
05
Phenotype

Clinical features

3 clinical features

The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.

Request access
06
Population genetics

GWAS signals

1 GWAS phenotype

Gene-associated GWAS phenotypes matching the disorder, with best SNP, score, risk-allele frequency and effect size.

Request access
07
Provenance

References & sources

7 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access