Genopathy
Gene-Disorder Association · Article
Gene
PIK3CA
Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha
Disorder
Adenocarcinoma
First reported 2004
Supporting publications 8
Key publication · gene–disorder Early involvement of the phosphatidylinositol 3-kinase/Akt pathway in lung cancer progression.American journal of respiratory and critical care medicine · 2004
Key publication · disorder Histologic changes produced by radiation in adenocarcinomas of the uterus; comparison with changes produced in squamous cell carcinomas of cervix.American journal of clinical pathology · 1950
Manually curated
Association Review

In brief

The association between PIK3CA (Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha) and Adenocarcinoma is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 0
Compounds 0
Trials 0
Publications 8
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
PIK3CA

The gene

3 source summaries

A gene summary alongside the source descriptions it was distilled from.

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04
Adenocarcinoma

The disorder

6 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
Literature

Reading

8 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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06
Provenance

References & sources

12 references

Every source and publication cited across this dossier, as one numbered reference list.

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