Gene-Disorder Association · Article
Gene
PNMT Phenylethanolamine N-Methyltransferase
×
First reported
2003
Supporting publications
1
Manually curated Approved treatment annotated
Association Review
In brief The association between PNMT (Phenylethanolamine N-Methyltransferase) and Hypertension, Essential is reported, with clinical genetic testing available.
Sources
1
Clinical variants
0
Symptoms
8
Compounds
1
Trials
1 of 18 via PNMT compounds
Publications
1
Contents
01
At a glance
Association overview A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.
Request access 02
Provenance
Evidence and sources 1 source
Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.
Request access 1 source summary
A gene summary alongside the source descriptions it was distilled from.
Request access 04
Hypertension, Essential
The disorder 11 database identifiers
The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).
Request access 05
Phenotype
Clinical features 3 clinical features
The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.
Request access 06
Interventions
Therapeutics 1 compound or drug
Gene-targeting drugs and associated compounds, with class, approval status, mechanism, indications and trials.
Request access 07
Human studies
Clinical trials 18 clinical trials
Clinical trials reached through the pair’s compounds, keeping disorder-targeting trials separate from other indications.
Request access 1 publication
Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.
Request access 09
Provenance
References & sources 8 references
Every source and publication cited across this dossier, as one numbered reference list.
Request access 
