PRKAR1A and Multiple Endocrine Neoplasia: Association Evidence

Gene-Disorder Association · Article

Gene

PRKAR1A

Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha

Disorder

First reported 2002

Supporting publications 1

Key publication · gene–disorder Loss of heterozygosity in parathyroid glands of familial hypercalcemia with hypercalciuria and point mutation in calcium receptor.The Journal of clinical endocrinology and metabolism · 2002

Key publication · disorder Multiple endocrine adenomas; report of 8 cases in which the parathyroids, pituitary and pancreatic islets were involved.The Journal of clinical endocrinology and metabolism · 1953

Manually curated

Association Review

In brief

The association between PRKAR1A (Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha) and Multiple Endocrine Neoplasia is reported, with clinical genetic testing available.

Sources 1

Clinical variants 0

Symptoms 1

Compounds 0

Trials 0

Publications 1

At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access

Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access

PRKAR1A

The gene

2 source summaries

A gene summary alongside the source descriptions it was distilled from.

Request access

Multiple Endocrine Neoplasia

The disorder

8 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access

Literature

Reading

1 publication

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

Request access

Provenance

References & sources

6 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access