Genopathy
Gene-Disorder Association · Article
Gene
PTPN11
Protein Tyrosine Phosphatase Non-Receptor Type 11
Disorder
Myeloproliferative Neoplasm
First reported 2005
Supporting publications 3
Key publication · gene–disorder The mutational spectrum of PTPN11 in juvenile myelomonocytic leukemia and Noonan syndrome/myeloproliferative disease.Blood · 2005
Key publication · disorder Biochemical studies in chronic myelocytic leukemia, polycythemia vera and other idiopathic myeloproliferative disorders.Blood · 1952
Manually curated
Association Review

In brief

The association between PTPN11 (Protein Tyrosine Phosphatase Non-Receptor Type 11) and Myeloproliferative Neoplasm is reported, with clinical genetic testing available.

Sources 1
Clinical variants 0
Symptoms 2
Compounds 0
Trials 0
Publications 3
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access
02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access
03
PTPN11

The gene

2 source summaries

A gene summary alongside the source descriptions it was distilled from.

Request access
04
Myeloproliferative Neoplasm

The disorder

10 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access
05
Literature

Reading

3 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

Request access
06
Provenance

References & sources

8 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access