PTPRO and Nephrotic Syndrome: Association Evidence | Genopathy

Gene-Disorder Association · Article

Gene

PTPRO

Protein Tyrosine Phosphatase Receptor Type O

Disorder

Nephrotic Syndrome

First reported 1998

Supporting publications 1

Key publication · gene–disorder Podocyte phenotypes as defined by expression and distribution of GLEPP1 in the developing glomerulus and in nephrotic glomeruli from MCD, CNF, and FSGS. A dedifferentiation hypothesis for the nephrotic syndrome.Experimental nephrology · 1998

Key publication · disorder The effects of ACTH and cortisone on the nephrotic syndrome.A.M.A. American journal of diseases of children · 1950

Manually curated

Association Review

In brief

The association between PTPRO (Protein Tyrosine Phosphatase Receptor Type O) and Nephrotic Syndrome is reported, with clinical genetic testing available.

Sources 1

Clinical variants 0

Symptoms 1

Compounds 0

Trials 0

Publications 1

01

At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

02

Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

03

PTPRO

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

04

Nephrotic Syndrome

The disorder

9 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

05

Literature

Reading

1 publication

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

06

Provenance

References & sources

4 references

Every source and publication cited across this dossier, as one numbered reference list.