Genopathy
Gene-Disorder Association · Article
Gene
SCUBE3
Signal Peptide, CUB Domain And EGF Like Domain Containing 3
Disorder
Prostate Cancer
First reported 1950
Key publication · disorder Endocrine control of prostatic carcinoma; clinical and statistical survey of 1,818 cases.Journal of the American Medical Association · 1950
Manually curated
Association Review

In brief

The association between SCUBE3 (Signal Peptide, CUB Domain And EGF Like Domain Containing 3) and Prostate Cancer is reported, with clinical genetic testing available.

Sources 1
Clinical variants 1
Symptoms 5
Compounds 0
Trials 0
Publications 0
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access
02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access
03
SCUBE3

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

Request access
04
Prostate Cancer

The disorder

20 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access
05
Phenotype

Clinical features

1 clinical feature

The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.

Request access
06
ClinVar and variant evidence

Genetic basis

1 clinical variant

ClinVar variants reported for this pair, with disorder-specific significance, review status, molecular consequence and origin.

Request access
07
Provenance

References & sources

7 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access