Genopathy
Gene-Disorder Association · Article
Gene
SIAE
Sialic Acid Acetylesterase
Disorder
Autoimmune Disease 6
First reported 1993
Supporting publications 1
Key publication · disorder Treatment effect of a traditional Chinese medicine, ren-shen-yang-rong-tang (Japanese name: ninjin-youei-to), on autoimmune MRL/MP-lpr/lpr mice.International journal of immunopharmacology · 1993
Manually curated
Association Review

In brief

The association between SIAE (Sialic Acid Acetylesterase) and Autoimmune Disease 6 is well established and manually curated, with its 4 contributing sources — 3 of them expert-curated — recording a known molecular basis, causative variation, and a susceptibility locus.

Sources 4
Clinical variants 5
Symptoms 0
Compounds 0
Trials 0
Publications 1
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

4 sources

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
SIAE

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

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04
Autoimmune Disease 6

The disorder

4 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
ClinVar and variant evidence

Genetic basis

5 clinical variants

ClinVar variants reported for this pair, with disorder-specific significance, review status, molecular consequence and origin.

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06
Literature

Reading

1 publication

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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07
Provenance

References & sources

6 references

Every source and publication cited across this dossier, as one numbered reference list.

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