Genopathy
Gene-Disorder Association · Article
Gene
SLC1A1
Solute Carrier Family 1 Member 1
Disorder
Schizophrenia 18
First reported 1977
Key publication · disorder Psychiatric morbidity among university students in Egypt.The British journal of psychiatry : the journal of mental science · 1977
Manually curated
Association Review

In brief

The association between SLC1A1 (Solute Carrier Family 1 Member 1) and Schizophrenia 18 is well established and manually curated, with its 3 contributing sources — 2 of them expert-curated — recording a known molecular basis, likely-pathogenic variants, and a susceptibility locus.

Sources 3
Clinical variants 4
Symptoms 0
Compounds 0
Trials 0
Publications 0
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

3 sources

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
SLC1A1

The gene

2 source summaries

A gene summary alongside the source descriptions it was distilled from.

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04
Schizophrenia 18

The disorder

7 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
ClinVar and variant evidence

Genetic basis

4 clinical variants

ClinVar variants reported for this pair, with disorder-specific significance, review status, molecular consequence and origin.

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06
Population genetics

GWAS signals

1 GWAS phenotype

Gene-associated GWAS phenotypes matching the disorder, with best SNP, score, risk-allele frequency and effect size.

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07
Provenance

References & sources

6 references

Every source and publication cited across this dossier, as one numbered reference list.

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