Genopathy
Gene-Disorder Association · Article
Gene
SMUG1
Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1
Disorder
Prostate Cancer
First reported 1950
Key publication · disorder Endocrine control of prostatic carcinoma; clinical and statistical survey of 1,818 cases.Journal of the American Medical Association · 1950
Manually curated
Association Review

In brief

The association between SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1) and Prostate Cancer is reported, with clinical genetic testing available.

Sources 1
Clinical variants 1
Symptoms 5
Compounds 0
Trials 0
Publications 0
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access
02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access
03
SMUG1

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

Request access
04
Prostate Cancer

The disorder

20 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access
05
Phenotype

Clinical features

1 clinical feature

The disorder’s clinical features (HPO) grouped by body system, each with observed frequency and penetrance.

Request access
06
ClinVar and variant evidence

Genetic basis

1 clinical variant

ClinVar variants reported for this pair, with disorder-specific significance, review status, molecular consequence and origin.

Request access
07
Provenance

References & sources

7 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access