Genopathy
Gene-Disorder Association · Article
Gene
SOD2
Superoxide Dismutase 2
Disorder
Microvascular Complications Of Diabetes 6
First reported 2003
Key publication · gene–disorder The polymorphism of manganese superoxide dismutase is associated with diabetic nephropathy in Japanese type 2 diabetic patients.Journal of human genetics · 2003
Key publication · disorder [Kimmelstiel-Wilson syndrome: diabetic nephropathy].La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris · 1950
Manually curated
Association Review

In brief

The association between SOD2 (Superoxide Dismutase 2) and Microvascular Complications Of Diabetes 6 is a manually-curated gene–disease association, with its 2 contributing sources — 1 of them expert-curated — recording a known molecular basis and a susceptibility locus.

Sources 2
Clinical variants 2
Symptoms 0
Compounds 0
Trials 0
Publications 0
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

2 sources

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
SOD2

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

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04
Microvascular Complications Of Diabetes 6

The disorder

7 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
ClinVar and variant evidence

Genetic basis

2 clinical variants

ClinVar variants reported for this pair, with disorder-specific significance, review status, molecular consequence and origin.

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06
Provenance

References & sources

4 references

Every source and publication cited across this dossier, as one numbered reference list.

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