Genopathy
Gene-Disorder Association · Article
Gene
TAB2
TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 2
Disorder
Dilated Cardiomyopathy
First reported 1954
Key publication · disorder Idiopathic cardiomegaly.Transactions of the American Clinical and Climatological Association · 1954
Manually curated
Association Review

In brief

The association between TAB2 (TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 2) and Dilated Cardiomyopathy is a manually-curated gene–disease association, with its 2 contributing sources — 1 of them expert-curated — recording pathogenic variants.

Sources 2
Clinical variants 1
Symptoms 0
Compounds 0
Trials 0
Publications 0
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

Request access
02
Provenance

Evidence and sources

2 sources

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

Request access
03
TAB2

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

Request access
04
Dilated Cardiomyopathy

The disorder

12 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

Request access
05
ClinVar and variant evidence

Genetic basis

1 clinical variant

ClinVar variants reported for this pair, with disorder-specific significance, review status, molecular consequence and origin.

Request access
06
Provenance

References & sources

4 references

Every source and publication cited across this dossier, as one numbered reference list.

Request access