Genopathy
Gene-Disorder Association · Article
Gene
TLX1
T Cell Leukemia Homeobox 1
Disorder
Precursor T-Cell Acute Lymphoblastic Leukemia
First reported 1991
Supporting publications 26
Key publication · gene–disorder The tcl-3 proto-oncogene altered by chromosomal translocation in T-cell leukemia codes for a homeobox protein.The EMBO journal · 1991
Key publication · disorder Influence of Incubation Solution on the Rate of Recovery of Pratylenchus brachyurus from Cotton Roots.Journal of nematology · 1971
Manually curated
Association Review

In brief

The association between TLX1 (T Cell Leukemia Homeobox 1) and Precursor T-Cell Acute Lymphoblastic Leukemia is a manually-curated gene–disease association, supported by a single expert-curated source.

Sources 1
Clinical variants 0
Symptoms 0
Compounds 0
Trials 0
Publications 26
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
TLX1

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

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04
Precursor T-Cell Acute Lymphoblastic Leukemia

The disorder

7 database identifiers

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
Literature

Reading

26 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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06
Provenance

References & sources

11 references

Every source and publication cited across this dossier, as one numbered reference list.

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