Genopathy
Gene-Disorder Association · Article
Gene
TRB
T Cell Receptor Beta Locus
Manually curated
Association Review

In brief

The association between TRB (T Cell Receptor Beta Locus) and Hereditary Chronic Pancreatitis is well established and manually curated, drawing on a single expert-curated source, which records pathogenic and likely-pathogenic variants.

Sources 1
Clinical variants 769
Symptoms 0
Compounds 0
Trials 0
Publications 94
01
At a glance

Association overview

A cited synthesis of the gene–disorder association, with a clinical-actionability summary where the evidence supports one.

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02
Provenance

Evidence and sources

1 source

Every contributing database and publication behind this association, with evidence type, strength, accessions and deep links.

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03
TRB

The gene

1 source summary

A gene summary alongside the source descriptions it was distilled from.

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04
Hereditary Chronic Pancreatitis

The disorder

The disorder’s summary, prevalence, aliases and cross-reference identifiers (OMIM, Orphanet, MONDO, ICD-10, MedGen).

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05
ClinVar and variant evidence

Genetic basis

769 clinical variants

ClinVar variants reported for this pair, with disorder-specific significance, review status, molecular consequence and origin.

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06
Population genetics

GWAS signals

1 GWAS phenotype

Gene-associated GWAS phenotypes matching the disorder, with best SNP, score, risk-allele frequency and effect size.

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07
Literature

Reading

94 publications

Publications linking the gene and the disorder, with title, authors, journal, year and citation metrics.

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08
Provenance

References & sources

11 references

Every source and publication cited across this dossier, as one numbered reference list.

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